It was by mere chance and great curiosity early on in my practice that I embarked on the adventure of learning about hormones, which eventually led to development of Seaside’s Healthy Aging Program. At the time nearly a decade ago, the demand for testosterone therapy for both men and women had already gained momentum amongst athletes, law enforcement workforce, and lay persons alike. Ordinarily a urologist, subspecialist with expertise on men’s health and genitourinary disorders prescribed testosterone. This clearly wasn’t enough to meet the call of millions of people looking to regain the fountain of youth, decelerate the process of aging, and attain a higher quality of life. Newer and better methods of testosterone replacement began hitting the market, guided by pharmaceutical giants, compounding pharmacies, urologic and endocrine societies, and last but not least innovative thinkers in the nascent and unregulated field of medicine, called Anti-Aging.
Seaside Designs Novel Testosterone Protocol for Testosterone Deficiency
At Seaside, we designed carefully planned protocols on various hormone replacement therapies, one being the DST or Daily Subcutaneous Testosterone therapy. At our 7th year mark, I realized not many people knew about this truly effective, and safe method of testosterone replacement for management of TD. I set out to accomplish one goal: let the world know about DST Method. With the help of my dedicated staff, we gathered the data on hundreds of patients treated in our facility from 2009-2016, recruited an awesome medical author and got a publication in a premier medical journal Frontiers in Bioscience. This endeavour was possible because of our loyal and staunch patients, whose quest for Healthy Aging was as enthusiastic as mine.
Frontiers In Bioscience, Elite, 10, 334-343, March 1, 2018
Daily subcutaneous testosterone for management of testosterone deficiency
Nasimeh Yazdani, Stacy Matthews Branch
Testosterone deficiency (TD) is a public health concern, a predictor of metabolic syndrome, and is associated with an increased all-cause and cardiovascular mortality. Testosterone deficiency in men is treated by a variety of methods including injectable testosterone compounds, patches, gels, pellets, and oral preparations. The use of testosterone alone has been linked to various adverse effects including, infertility, testicular atrophy, erythropoiesis, and gynecomastia. To determine the effectiveness of therapy using the Daily Subcutaneous Testosterone (DST) method in combination with human chorionic gonadotropin (hCG) and an aromatase inhibitor (anastrozole), a retrospective analysis was conducted of men diagnosed and treated for TD. Changes in testosterone, estradiol, sex hormone binding globulin (SHBG), luteinizing hormone (LH), follicle stimulating hormone (FSH), dihydrotestosterone (DHT), dehydroepiandrosterone sulfate (DHEA-S), prostate-specific antigen (PSA), pregnenolone, and hemoglobin were determined. There was a significant increase in total testosterone, free serum testosterone, and direct free testosterone in the testosterone treated patients. There was a significant increase in total and free testosterone levels with the DST method combined with hCG and anastrozol, suggesting that DST therapy is a viable option to restore testosterone levels in men.