We all seek the maintenance and/or restoration of health and youth in some way or another. Medical science has played a central and crucial role in providing both drastic and subtle means to regain physical appearance altered by illness, trauma, or the aging process. Even more desirable is a way to avoid invasive procedures while realizing the intended positive outcomes. A rapidly emerging medical application that harnesses the power of products from the very cells responsible for the development of new tissues is called exosome therapy.
What are exosomes in Regenerative Medicine?
Different from stem cells, exosomes are the nanoparticles that are pinched off from cells in the shape of a vesicle. Inside each vesicle are rich sources of protein, DNA, and RNA from the originating cells. These vesicles can be taken up by other distant cells and affect the function of these target cells. Although exosomes are secreted by all cell types, those that are derived from stem cells (undefined cells that can develop into any cell type) have a powerful role in regenerative medicine by facilitating healing and repair processes (1).
Exosome therapy entails the medical use of exosomes for drug delivery, as well as regenerative or restorative measures to treat conditions such as tissue injury, osteoarthritis, chronic inflammation, fibromyalgia, degenerative diseases, and even cancer. Given the regenerative capabilities, exosomes are also used in medical aesthetics. Two areas of aesthetics where research has revealed the utility of exosome therapy are facial aesthetics and hair restoration.
Exosomes for Medical Aesthetics
There are commercially available exosome products derived from mesenchymal stem cells taken from donated adult bone marrow. Doctors can use these stem cell–derived exosomes for skin reconstruction (2, 3, 4). Exosomes can be used to significantly increase skin collagen and elastin. This can result in changing the appearance of scars, decrease skin irritation, help with acne, address sagging skin, and reduce age spots and wrinkles. One way exosomes can be used in a facial procedure is by microneedling with exosomes. Exosomes are diffused over outer skin layers releasing growth factors to injured skin, thereby activating an enhanced wound healing process, and tissue remodeling.
In addition to skin improvement applications, studies have shown that exosomes can successfully be used in the hair restoration arena. Unlike other common treatments for alopecia (hair loss), exosome therapy(Regenerative Medicine) promotes hair growth without reports of adverse effects (5). Exosomes injected into scalp arrive at dermal papillae, located at the bottom of hair follicles, to help regrow hair (6).
Exosomes have versatile applications in many areas of medical therapeutics, and their successful and minimally invasive applications for medical aesthetics continues to expand as more is discovered about these powerful biologics.
See what our patients are saying about Regenerative Medicine that is Exosome Therapy
“The whole process went smooth and very little discomfort.
I healed quickly from the injection sites and noticing more hair growth on top of my scalp!”
– Cameron A.
“We decided to offer exosome therapy because it’s the essence of regenerative medicine short of infusing stem cells. Xoflo is a reputable system we trust wholeheartedly to provide our patients with the best exosomes available in the market. There is a lot of promise in this growing field and we’re excited to be a part it.”
– Dr. Nasimeh Yazdani, M.D.
Click below to watch Dr. Yazdani perform Exosome Therapy
on a patient suffering from male pattern baldness: