Restless Leg Syndrome is a condition characterized by an uncontrollable urge to move the legs, with onset usually occurring in the evenings. RLS can be caused by various health conditions, but some of the mystery of its origins have been elucidated by the link found between RLS and iron levels.
Studies have increasingly found that the most consistent finding and greatest risk factor for Restless Leg Syndrome is iron deficiency.
RLS caused by iron-deficiency anemia is known as secondary restless legs syndrome. Symptoms tend to worsen in correlation with decreasing iron levels.
Part of the link between iron levels and RLS is related to the role of iron in producing dopamine in the brain, in the substantia nigra region. Studies have found that iron disregulation occurs in brains of individuals with RLS, especially in cells that produce dopamine, a neurotransmitter that plays a role in muscle control and movement.
RLS tends to worsen in the evenings in concert with falling dopamine levels as the day wears on.
Patients with RLS are strongly encouraged to have their serum ferritin levels evaluated. IV Iron is a great way to increase iron levels effectively and efficiently.
Patients should aim for a ferritin level of 100, instead of the typical 40 that is specified on lab reference images.
In fact, it has been found that even individuals with normal iron levels have been found to respond well to iron replacement.
The role of IV iron in all sorts of health conditions continues to be supported by scientific research. As awareness of its promise and benefits spreads, the treatment can help to improve the lives and comfort of individuals struggling with RLS.